UNIV - Post Doctoral Scholar- Microbiology and Immunology

Job Description Summary

The Paczesny laboratory is seeking highly motivated candidates for a post-doctoral fellowship studying tumor immunology including with hematopoietic cell transplantation to treat myeloid malignancies. The major interests of the lab are discovering and validating new biomarkers and immune cells subsets in tumor immunology, generating new cell-based immunotherapies such as T9IL33 recently published in the Journal of Experimental Medicine and highlighted in the New England Journal of Medicine, as well as developing new small molecules based on discovery of novel targets. In this position, you will have the opportunity to develop and lead projects using several cutting-edge model systems including hematopoietic cell transplantation and novel xenograft in vivo systems, and primary patient samples. You will also gain extensive experience and training in proteomics, hematopoietic cell transplantation biology, and pre-clinical study development.

Entity

Medical University of South Carolina (MUSC - Univ)

Worker Type

Employee

Worker Sub-Type​

Research Grant

Cost Center

CC000981 COM M&I Operations CC

Pay Rate Type

Salary

Pay Grade

University-00

Pay Range

$0 - $0 - $0

Scheduled Weekly Hours

40

Work Shift

Job Description

Job Duties:

35% - Develop and lead projects using several cutting-edge model systems including hematopoietic cell transplantation and novel xenograft in vivo systems, and primary patient samples. Each project leading to a presentation at a national meeting as well as manuscript of impact factor > 6. - (Essential)

35% - Train in proteomics, hematopoietic cell transplantation biology, and pre-clinical study develoment. Similarly the outcomes will lead to a publishable manuscript - (Essential)

25% - Perform immunology techniques including ELISAs, flow-based cytokine determination, cellular proliferation and cytotoxicity assays including for collaborative work on multi-institutional grants. - (Essential)

5% - Perform other essential duties as requested. These will include maintain animal colonies, collaborate with DLAR to provide the best animal care, update IACUC and IBC protocols, order supplies for the laboratory. - (Essential)

The Medical University of South Carolina (MUSC) is located in the beautiful historic district of Charleston (ranked #1 travel destination in the U.S.) bounded by the Atlantic Ocean and beautiful beaches to the east, and national forests and wildlife refuges to the north and south. MUSC is the state’s top-ranked medical center. The Medical University of South Carolina is a leading medical research university that fosters excellence and attracts world-class talent to innovate today and prepare leaders for the future. The Medical University of South Carolina is an Equal Opportunity Employer. MUSC does not discriminate on the basis of race, color, religion or belief, age, sex, national origin, gender identity, sexual orientation, disability, protected veteran status, family or parental status, or any other status protected by state laws and/or federal regulations.

All qualified applicants are encouraged to apply and will receive consideration for employment based upon applicable qualifications, merit and business need.

 

Application materials should be addressed to the department chair:

Sophie Paczesny, MD, Ph.D.

Chair Department of Microbiology and Immunology

Medical University of South Carolina

Hollings Cancer Biology Immunology Program co-leader

Sally Abney Rose Endowed Chair in Cancer Stem Cell Biology

Basic Sciences Building, Ste 203

173 Ashley Ave, MSC 504

Charleston, SC 29425

paczesns@musc.edu

Preferred Experience & Additional Skills: Successful applicants will have a Ph.D. or M.D./Ph.D. with substantial hands-on research experience in immunology; a strong publication record in recognized peer-reviewed journals; experience with multicolor flow cytometry and in immunology techniques including ELISAs, flow-based cytokine determination, cellular proliferation and cytotoxicity assays; experience with animal models of bone marrow transplantation is required; be meticulous at planning, executing, and organizing the results for large scale assays. Must also be capable of taking initiative, work independently and in a collaborative setting. Excellent written and verbal communication skills are required, as are excellent organizational skills and knowledge of proper scientific record keeping as well as being comfortable in a fast-paced environment and able to adjust workload based upon changing priorities.

Physical Requirements:  (Note: The following descriptions are applicable to this section: Continuous 6-8 hours per shift; Frequent - 2-6 hours per shift; Infrequent - 0-2 hours per shift)
Ability to perform job functions in an upright position. (Continuous) Ability to perform job functions in a seated position. (Continuous) Ability to perform job functions while walking/mobile. (Frequent) Ability to climb stairs. (Infrequent) Ability to work indoors. (Continuous) Ability to work in all cold temperature extremes, i.e. spot coolers. (Frequent) Ability to bend at the waist. (Frequent) Ability to twist at the waist. (Frequent) Ability to perform 'pinching' operations. (Continuous) Ability to fully use both hands/arms. (Continuous) Ability to perform repetitive motions with hands/wrists/elbows and shoulders. (Continuous) Ability to fully use both legs. (Continuous) Ability to reach in all directions. (Continuous) Possess good finger dexterity. (Continuous) Ability to maintain tactile sensory functions. (Continuous) Ability to maintain good olfactory sensory function. (Continuous) Ability to lift and carry 15 lbs., unassisted. (Frequent) Ability to lift objects, up to 15 lbs., from floor level to height of 72 inches, unassisted. (Frequent) Ability to lower objects, up to 15 lbs., from height of 72 inches to floor level, unassisted. (Frequent) Ability to push/pull objects, up to 15 lbs., unassisted. (Infrequent) Ability to lift and carry objects up to 15 lbs. a distance of five (5) floors and to outlying buildings. (Frequent) Ability to maintain 20/40 vision, corrected. (Continuous) Ability to see and recognize objects close at hand. (Continuous) Ability to see and recognize objects at a distance. (Continuous) Ability to match or discriminate between colors. (Continuous) Ability to determine distance/relationship between objects; depth perception. (Continuous) Good peripheral vision capabilities. (Continuous) Ability to maintain hearing acuity, with correction. (Continuous) Ability to perform gross motor functions with frequent fine motor movements. (Continuous) Ability to be qualified physically (by medical personnel) for respirator use, initially and annually. Ability to work alone in isolated areas, such as darkrooms. (Frequent)
Additional New Requirements: Ability to obtain and maintain a valid drivers license. Computer literacy. Ability to work rotating shifts as required. Ability to work overtime as required. Ability to learn and use new processes, tools and equipment as required.

Additional Job Description

N/A

If you like working with energetic enthusiastic individuals, you will enjoy your career with us!

The Medical University of South Carolina is an Equal Opportunity Employer. MUSC does not discriminate on the basis of race, color, religion or belief, age, sex, national origin, gender identity, sexual orientation, disability, protected veteran status, family or parental status, or any other status protected by state laws and/or federal regulations. All qualified applicants are encouraged to apply and will receive consideration for employment based upon applicable qualifications, merit and business need.

Medical University of South Carolina participates in the federal E-Verify program to confirm the identity and employment authorization of all newly hired employees. For further information about the E-Verify program, please click here: http://www.uscis.gov/e-verify/employees