UNIV-Research Assistant Professor-Department of Biochemistry

Job Description Summary

Seeking experienced and self-motivated candidate for the position of Research Assistant Professor available in the laboratory of Dr. Ozgur Sahin. Dr. Sahin is a Professor and SmartState Endowed Chair in the Department of Biochemistry & Molecular Biology at MUSC. Sahin’s laboratory focuses on identifying the mechanisms of drug resistance/metastasis and target these resistance/metastasis-driving factors with either own developed compounds or available drugs to overcome resistance/block metastasis. The successful candidate will work at the intersection of overcoming resistance to therapy and metastasis in breast cancer. The candidate will handle various Biochemistry, Cell and Molecular Biology tools and techniques, Western blots, co-IP, qPCR, flow cytometry, fluorescence microscopy, cell-based growth and apoptosis assays, CRISPR-Cas9 gene knockout and high-throughput sequencing technologies, such as single cell RNA-seq and ATAC-seq. Furthermore, the candidate will prepare grants and assist the PI of the lab on writing grants proposals in addition to supervising junior members of the lab.

Entity

Medical University of South Carolina (MUSC - Univ)

Worker Type

Employee

Worker Sub-Type​

Faculty

Cost Center

CC000954 COM BIOCHEM Operations CC

Pay Rate Type

Salary

Pay Grade

University-00

Pay Range

0.00 - 0.00 - 0.000

Scheduled Weekly Hours

40

Work Shift

Job Description

Job Description:

Seeking experienced and self-motivated candidate for the position of Research Assistant Professor available in the laboratory of Dr. Ozgur Sahin. Dr. Sahin is a Professor and SmartState Endowed Chair in the Department of Biochemistry & Molecular Biology at MUSC. Sahin’s laboratory focuses on identifying the mechanisms of drug resistance/metastasis and target these resistance/metastasis-driving factors with either own developed compounds or available drugs to overcome resistance/block metastasis. The successful candidate will work at the intersection of overcoming resistance to therapy and metastasis in breast cancer. The candidate will handle various Biochemistry, Cell and Molecular Biology tools and techniques, Western blots, co-IP, qPCR, flow cytometry, fluorescence microscopy, cell-based growth and apoptosis assays, CRISPR-Cas9 gene knockout and high-throughput sequencing technologies, such as single cell RNA-seq and ATAC-seq. Furthermore, the candidate will prepare grants and assist the PI of the lab on writing grants proposals in addition to supervising junior members of the lab.

MUSC Education and Experience Requirements:

Requires a PhD, with significant scientific accomplishments and a track record of publishing. Minimum two first author papers in high impact journals.

Preferred Experience and Training:

· Strong biochemistry and molecular biology expertise.

· Analyze and interpret data and write the results.

· Write manuscripts.

· Design and write grants for extramural support both independently and as a team with Dr. Sahin.

· Teach laboratory procedures to other students and postdocs in the laboratory.

Job Duties:

1. Provide unique leadership in molecular biology & biochemistry (continuum of technologies and direct mentoring laboratory skills to younger members) in the laboratory.

30% of total effort

2. Conduct in vitro experiments to overcome therapy resistance and block metastasis by combining several cell-based assays and doing detailed biochemistry experiments.

30% of total effort

3. Preparation of data for dissemination; duties include preparing figures and writing manuscripts, presenting data at local and national conferences, and preparing grants and assisting the PI of the lab on writing grants proposals.

30% of total effort

4. Maintain accurate detailed records of all experiments performed on a daily basis.

10% of total effort

Additional Job Description

Physical Requirements: (Note: The following descriptions are applicable to this section: Continuous - 6-8 hours per shift; Frequent - 2-6 hours per shift; Infrequent - 0-2 hours per shift) Ability to perform job functions in an upright position. (Continuous) Ability to perform job functions in a seated position. (Continuous) Ability to perform job functions while walking/mobile. (Frequent) Ability to climb stairs. (Infrequent) Ability to work indoors. (Continuous) Ability to work in all cold temperature extremes, i.e. spot coolers. (Frequent) Ability to bend at the waist. (Frequent) Ability to twist at the waist. (Frequent) Ability to perform 'pinching' operations. (Continuous) Ability to fully use both hands/arms. (Continuous) Ability to perform repetitive motions with hands/wrists/elbows and shoulders. (Continuous) Ability to fully use both legs. (Continuous) Ability to reach in all directions. (Continuous) Possess good finger dexterity. (Continuous) Ability to maintain tactile sensory functions. (Continuous) Ability to maintain good olfactory sensory function. (Continuous) Ability to lift and carry 15 lbs., unassisted. (Frequent) Ability to lift objects, up to 15 lbs., from floor level to height of 72 inches, unassisted. (Frequent) Ability to lower objects, up to 15 lbs., from height of 72 inches to floor level, unassisted. (Frequent) Ability to push/pull objects, up to 15 lbs., unassisted. (Infrequent) Ability to lift and carry objects up to 15 lbs. a distance of five (5) floors and to outlying buildings. (Frequent) Ability to maintain 20/40 vision, corrected. (Continuous) Ability to see and recognize objects close at hand. (Continuous) Ability to see and recognize objects at a distance. (Continuous) Ability to match or discriminate between colors. (Continuous) Ability to determine distance/relationship between objects; depth perception. (Continuous) Good peripheral vision capabilities. (Continuous) Ability to maintain hearing acuity, with correction. (Continuous) Ability to perform gross motor functions with frequent fine motor movements. (Continuous) Ability to be qualified physically (by medical personnel) for respirator use, initially and annually. Ability to work alone in isolated areas, such as darkrooms. (Frequent) Additional New Requirements: Ability to obtain and maintain a valid drivers license. Computer literacy. Ability to work rotating shifts as required. Ability to work overtime as required. Ability to learn and use new processes, tools and equipment as required.

If you like working with energetic enthusiastic individuals, you will enjoy your career with us!

The Medical University of South Carolina is an Equal Opportunity Employer. MUSC does not discriminate on the basis of race, color, religion or belief, age, sex, national origin, gender identity, sexual orientation, disability, protected veteran status, family or parental status, or any other status protected by state laws and/or federal regulations. All qualified applicants are encouraged to apply and will receive consideration for employment based upon applicable qualifications, merit and business need.

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